Lefty- I do that on a fairly regular basis. Decievers, Bangers, Seaducers, Surf Candies, Snake Flies, Clousers,......the list goes on and on. In addition, I've been tying up some small and sparse versions of Juro's Real Eel in smoke and bronze for an upcoming trip to the Cape, but couldn't help notice that they'd probably be killer on bass, especially smallmouths. I also occasionally find myself taking some of my so-called largemouth or pike flies and using them for stripers and blues.
I think that instead of rigidly defining my flyboxes by fresh vs. salt or by species type, I'm gonna just label them all "STUFF". That should keep my mind open. Seriously though, go for it. I've caught some awfully good bass on flies that were originally intended for the salt.