I grew up in the Hazleton, PA area (I left there in 1979 at age 25) and fished the West Branch Delaware and the mainstem from Hancock down to Callicoon a lot. I had many great days fishing hatches for its wild trout and its shad. Some of my best memories are of fishing the Golden Drakes, sulfers, and blue winged olives, along with the huge caddis egg-laying flights on summer evenings. I also had some very memorable nights fishing for large browns on the West Branch.
Since the Delaware and West Branch Delaware are such large rivers and you waded them, I doubt you would find wading most any river difficult.