If at all possible.......
I would try to do a day or half day with a guide...why ? Well DIY without some experience can be a frustrating experience. And bonefishing is such a great sport that it may turn you off if you dont score. I have never fished the Keys for bones...just the Bahamas.....I have been told some of the Kwan type patterns work well in the keys......post a trip report when you get back !!